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Web-Based Curriculum & Reference  
Editors
Kurt J. Pfeifer, MD, FACP
Steven L. Cohn, MD, FACP
 
Medical College of Wisconsin
State University of New York - Downstate
 
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  Pregnancy
Michael P. Carson, MD & David A. Halle, MD
 
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    RISK MANAGEMENT

    Postoperative Hypertension
       

    Internists may be called to treat hypertension in women who underwent Caesarean deliveries for severe preeclampsia (see criteria on right).

     
    TREATMENT
    • Labetalol
      • Compatible with breastfeeding
      • Use for SBP>170, DBP>100 not related to pain
      • PO dose: 200 mg BID-TID (max 2400 mg/day)
      • IV bolus dose: 20 mg & double to up to 80 mg if inadequate response (10-20 min between doses)
      • Continuous IV dose: start at 1 mg/kg/hr
    • Methyldopa
      • Literature suggests exposed children do NOT have developmental effects.
      • PO dose: 250 mg BID-TID (max 3000 mg/day - increase dose every 2 days as needed).
    • Other options
      • Beta-blockers acceptable - metoprolol preferred over atenolol.
      • Nifedipine acceptable & used for preterm uterine contractions.

     
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    PREECLAMPSIA
    Diagnostic Crieria
    • New SBP>140 or DBP>90
    • Proteinuria >300 mg/24 hrs or more than trace protein on urine dip analysis
    Other Findings
    • Headache
    • Visual changes
    • Right upper quadrant abdominal pain
    • Facial and hand edema

    In urgent settings, do not delay care for hypertension. Treat the mother and use medications and/or treatments with which you are familiar.

     
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